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Definition:
Severe acute respiratory syndrome (SARS) is a viral respiratory infection. It is caused by a coronavirus. SARS is predominantly transmitted through close person-to-person contact, especially via respiratory droplets produced when an infected person coughs or sneezes and deposited on the mucous membranes of the mouth, nose, or eyes of the bystanders. The incubation period typically ranges from 2-10 days. As the virus can survive to up to 72 hours at the contaminated surfaces, it can also be spread when a person touches a surface or object contaminated with infectious droplets and then touches his or her mouth, nose, or eyes. In Hong Kong, there were 1755 confirmed cases of SARS and 386 cases are healthcare workers and the death toll was 299.
Who is at risk?
Symptoms:
Treatment:
Options include
Thus far, there is no international agreement to the best treatment regime. Antibiotics are ineffective for the primary disease and the Ribavirin/steroid treatment in Hong Kong had variable response rates and complications.
Research:
Prevention:
Definition:
Schizophrenia is a disease of the brain which manifests as a psychiatric illness. Patients often have terrifying symptoms such as hearing internal voices not heard by others, or believing that other people are reading their minds, controlling their thoughts, or plotting to harm them.
Who is at risk?
Approximately 1% of the population develops schizophrenia during lifetime. People who have a close relative with schizophrenia are more likely to develop the disorder, but the genetic transmission is still poorly understood. Other constitutional factors such as the physical built, early childhood experiences, psychological and social stresses and physical illnesses can contribute.
Symptoms:
Symptoms may develop very gradually, or may strike dramatically within days. Symptoms can be classified into negative and positive symptoms:
Treatment:
A group of drugs called "antipsychotic drugs" are very useful in controlling some symptoms of schizophrenia. These drugs may have side effects such as drowsiness and abnormal movements. Newer antipsychotics may be better tolerated. Long acting injected preparations are useful in uncooperative patients.
Apart from drugs, psychotherapy and psychosocial treatment may also be used.
Prevention:
There is no way to prevent schizophrenia as the cause of the disease is still poorly understood. The community should work towards diagnosing and treating the disease early. We should also prevent relapses by ensuring that patients are compliant with the prescribed medication and provide good social and rehabilitation support to families.
Definition:
Septum is a wall partition. A septal defect is a hole in the partition.
The upper two chambers of the heart, called the atria, are separated by the atrial septum; and the lower two chambers, called ventricles, by the ventricular septum.
A patient suffering from atrial septal defect is having a hole in the atrial septum, similarly with ventricular septal defect.
Who is at risk?
Most cases of septal defects are congenital, and occur by chance as the fetus develops. The risk of having a child with congenital heart disease in general is 1% and increases to 2% if you already have one child with the condition. No cause can be identified in most cases, although the following conditions are known to be associated.
Statistically, septal defects occur more often if the mother is abusing alcohol, has poor nutrition, or is suffering from poorly controlled diabetes.
Symptoms:
Babies born with small septal defects may not have any symptoms. Symptoms may not appear until adolescence or adulthood especially with atrial septal defects. Often, a doctor picks up a murmur (a rumbling sound as blood is flowing through the defect) or abnormal heart sounds incidentally during routine examination.
When the defects are large, the following symptoms can occur during infancy or childhood.
Treatment:
When a septal defect is suspected, doctors need to confirm the diagnosis and assess its severity with tests. This would often include an echocardiogram (echo) - which uses sound waves to locate the hole and find out the size and blood flow.
One of the following strategies may be recommended depending on the patient's condition and results of tests:
Prevention:
Most cases of congenital septal defects are chances of nature, and little can be done to avoid them. You should of course avoid the known risk factors. Screening tests are available in early pregnancy for certain chromosome disorders, which can occur with septal defects.
Definition:
Commonly called blood poisoning or sepsis, septicaemia is caused by toxins or bacteria circulating in the blood. The presence of bacteria or toxins in the blood activates severe inflammatory responses and affects blood coagulation. These cause failure in multiple organs. It is a serious, rapidly progressive, life-threatening infection.
Who is at risk?
The following categories have the highest risk of having septicaemia:
Septicaemia is a major cause of death in intensive care units worldwide, with mortality rates that range from 20% to 60%.
Symptoms:
Septicaemia often begins with spiking fevers and chills though some patients may have body temperature below normal. The patient may complain of general pains and aches, or may have abdominal pain and vomiting. He looks severely ill and is breathing rapidly. Soon he becomes confused, with a weak, rapid pulse and a falling blood pressure. Red spots may appear in the skin, as a result of bleeding into the skin.
Treatment:
Successful treatment of septicaemia depends on:
Prevention:
A bacterium called Group B Streptococcus carried in mother's birth canal is a common cause of septicaemia in newborn babies. Screening and treatment of infected pregnant women can prevent the disease in newborn.
For infants and children, there are effective vaccines against bacteria such as Haemophilus influenza type b (a germ that causes meningitis) and pneumococcus (a germ that causes pneumonia) which are common causes of septicaemia in children. These are available in private clinics and hospitals in Hong Kong. Early, appropriate treatment of localized infections can prevent septicaemia.
Definition:
Sinusitis is inflammation of the sinus cavities. The sinus cavities are air-filled spaces in the skull. Depending on the severity of the infection, often little or no treatment is needed and 70% of sufferers will feel better within a week Acute sinusitis lasts for less than three weeks. Chronic sinusitis is diagnosed when symptoms last for at least 3 months. Recurrent sinusitis refers to repeated bouts of acute sinusitis.
Who is at risk?
Symptoms:
Treatment:
Prevention:
Definition:
Skin cancer is a disease in which cancer (malignant) cells are found in the outer layers of your skin. Your skin protects your body against heat, light, infection, and injury. It also stores water, fat, and Vitamin D. Skin cancer falls into two broad areas:
Although skin cancer can occur in people of all races, those with darker skin typically have a lower risk because their skin contains more of the pigment melanin, which protects against skin cancer.
Who is at risk?
Symptoms:
The most common symptoms are
Treatment:
Various modality of treatment are used for most skin cancers. They are:
Prevention:
Prevention must begin in childhood. That's because most people get about 50% of their lifetime sun exposure before age 18.
Practical measures to prevent skin cancer include:
Definition:
Historically, smallpox is a highly contagious disease that is caused by a deadly virus called Variola. A virulent strain of the virus typically kills 20 to 40 % of those infected. Those surviving the disease are left with and persistent skin scarring known as pockmarks. Scarring in the eyes can cause blindness.
Who is at risk?
The last naturally occurring case in the world was in Somalia in 1977. The WHO has announced that the Smallpox virus has successfully been eradicated in nature since the virus cannot survive onside human bodies in nature.
It doesn't follow that nobody is at risk now. Samples of the virus are still kept in research laboratories. Scientists, medical professionals and technicians working in such research facilities would be vulnerable if accident happens. There are also concerns that the virus could be used by terrorists and in biological warfare.
Symptoms:
Symptoms appear about 7 to 17 days after exposure and starts with high fever, headache and body aches. A rash follows two to three days later, which spreads and progresses to become raised bumps with severe blistering in the following 10 to 14 days. The blisters scab and fall off after about three weeks, leaving a pitted scar.
Treatment:
Treatment is supportive, there being no cure for smallpox. Vaccination within 3 days of exposure may prevent or lessen the severity of the disease.
Prevention:
Routine vaccination against smallpox among the general public was stopped in all countries because it was no longer necessary. The vaccine is still given to those working in research laboratories and sometimes to the military.
Definition:
Apnea means cessation of breathing. Sleep Apnea is defined as a pause of breath lasting ten seconds or more during sleep.
There are two main types of sleep apnea:
Obstructive Sleep Apnea (OSA):causes collapse of the upper air during sleep
Central Sleep Apnea:the brain fails to send the appropriate signals to move the respiratory muscles.
Since central sleep apnea is rare, people use the term sleep apnea loosely to mean OSA.
Who is at risk?
Symptoms:
Loud snoring
Obstructive sleep apnea is usually associated with snoring. The snoring proceeds at a regular pace for a period of time, often becoming louder, but is then interrupted by a long silent period with no breathing.
Breathing cessation during sleep (Apnea)
If the duration of breath holding exceeds 10 seconds, it is called apnea. Patients may become awake gasping for breath.
Morning headache
Since sleep is fragmented, the patient wakes up un-refreshed, with vague symptoms such as headache, tiredness, dry mouth and throat.
Excessive daytime sleepiness (hypersomnia)
Patient may fall asleep during business meetings, eating or even driving
Treatment:
Continuous positive airway pressure (CPAP)
This is a machine that delivers air pressure through a mask placed over the nose during sleep to keep the upper airway passages open.
Oral appliances
Devices may be designed by dentists to keep the jaw forward. They can relieve snoring and mild obstructive sleep apnea.
Surgical procedures
The most common type of surgery recommended by experts involves removing excessive soft tissues from the back of the mouth and top of the throat along with the tonsils and adenoids.
Prevention:
Definition:
Strabismus is sometimes known as crossed eyes, walleye, lazy eye or squint. The eyes do not point to the same direction. While one eye is looking straight ahead, the other may be looking up, down, in or out.
Who is at risk?
Strabismus is most common in children. Often there's no known cause, though sometimes the condition runs in families. Children with strabismus may also be farsighted, with both eyes affected asymmetrically.
Babies born prematurely and requiring high levels of oxygen have an increased risk of strabismus. Strabismus can also occur in children with neurological disorders. It is also common in children recovering from birth trauma, meningitis or brain bleeding. Patients with brain tumors may suffer from strabismus if the nerves controlling eye movements are interfered with. In adults, strabismus can also occur as a result of diabetes, or when a tumor grows around the eye.
Symptoms:
The eyes do not point to the same direction. While one eye is looking straight ahead, the other may be looking up, down, in or out.
Treatment:
A child with strabismus would receive a different image from each eye. With time the brain would learn to ignore the weak eye. Even when the vision of the weak eye has been restored, the patient's brain would not be able to "see". This permanent loss of vision is called amblyopia.
So the purpose of principle of treatment is to encourage the child to use the weaker eye by patching up the good side. Corrective spectacles need to be prescribed early. Surgery can correct strabismus in older children, but any loss in vision cannot be recovered.
Prevention:
Although strabismus cannot be prevented, its consequence can, provided the condition is detected early and treated properly. That's why every check-up should include a screening test for strabismus.
Definition:
Systemic lupus erythematosus (SLE) is a chronic immunological disorder. The patients' immune system is attacking and causing harm to their own organs. The skin and the joints are most commonly affected, but no organ is exempted. Accumulation of immune products can also damage small blood vessels and the kidneys.
Who is at risk?
SLE is more common in certain ethnic groups, including the Chinese. A family history of SLE would increase the risk. The exact genetic mechanism is still uncertain. If a person has an identical twin suffering from SLE, the chance of having the disease is about 30 to 50%. SLE can affect all age groups and both sexes, but is most common in women aged 20-45 years. The disease can get worse with pregnancy.
Symptoms:
The most common early symptoms are joint pain, fever and skin rash. Typically the rash is distributed over both cheeks, like a butterfly. Virtually any organ, including the heart, lungs, the gut and the blood, may be involved as the disease progresses. There is wide variation in the degree of severity. The chronic disease is marked by unpredictable periods of remissions and flares. When the brain and kidneys are involved, the disease is life-threatening.
Treatment:
Very mild cases may just need pain-killers and rest. Skin rash may respond to steroid creams. Some patients, especially those with joint pains, may require drugs related to aspirin as anti-inflammatory agents. Severe cases often require steroids given systemically. Those severely ill with the disease may be helped with anti-cancer drugs.
Prevention:
Most cases of SLE are not preventable as the exact mechanism of the disease is still unknown. Drugs that can give rise to symptoms of SLE should be avoided whenever possible. Patients should avoid exposure to the sun and UV light. Combined contraceptive pills can trigger a flare up in patients with SLE.
Definition:
This is a contagious skin disease caused by a parasitic mite. The mite burrows into the skin and causes an intensely itchy rash.
Who is at risk?
Symptoms:
Treatment:
Scabies can be treated with topical medicine applied to the skin. Many chemicals can kill the mite, but the doctor needs to consider the patient's age and sensitivity in order to prescribe the right treatment. The medication needs to be applied from neck to toe after bathing and must be remained on the skin overnight before being washed off. Sometimes a second application may be needed. The rash and itchiness may linger for weeks after treatment. Close family members and all sexual partners must be treated at the same time even they have no symptoms.
Prevention:
Definition:
Infections in the lungs caused by the bacteria Streptococcus pneumoniae. The bacteria can live in our upper respiratory tract and may invade into one or more lobes of the lung. The disease frequently occurs after viral upper respiratory tract infections such as influenza.
Who is at risk?
Symptoms:
Treatment:
Treatment with antibiotics, such as penicillin, is usually effective if the disease is diagnosed early. However, the incidence of penicillin-resistance is rapidly increasing. More powerful and expensive drugs are necessary in such cases.
Prevention:
There are two kinds of vaccines. "Polysaccharide vaccines" are made from polysaccharide antigens (sugar capsules) purified from the bacteria. It is not very effective in small children. Those younger than two should receive "conjugate vaccines" which are made by attaching a protein molecule into the polysaccharide antigen to boost immunity.
Pneumococcal vaccine was introduced into the Childhood Immunisation Programme in Hong Kong in September 2009. Newborns should receive a standard 3-dose primary series at 2nd, 4th and 6th months of age with a booster dose at 12-15th months. Those above 65 years old are also entitled to government subsidy scheme to be vaccinated.